Lymphadenopathy in Brucellosis

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Cytokine Gene Polymorphism in BCG Lymphadenopathy

Background: Tumor necrosis factor-beta or lymphotoxin-alpha (LT-α), IL-4 and IL-10 are determining factors in immunity against BCG.  Allelic polymorphisms in the regulatory regions of their genes affect the rate of cytokine production and therefore, the host’s ability in BCG containment. Objective: To study the prevalence of –590 (C/T) and –592 (C/A) allelic distribution of IL-4 and IL-10 promo...

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ژورنال

عنوان ژورنال: BMJ

سال: 1949

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.4631.787